Integrative Cell Biology: Katanin at the Crossroads
نویسنده
چکیده
A new study showing a functional and physical interaction between the ROP effector RIC1 and the microtubule severing enzyme katanin brings together auxin signaling and microtubule ordering in Arabidopsis pavement cells.
منابع مشابه
Cell Migration: Katanin Gives Microtubules a Trim
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Accurate control of spindle length is a conserved feature of eukaryotic cell division. Lengthening of mitotic spindles contributes to chromosome segregation and cytokinesis during mitosis in animals and fungi. In contrast, spindle shortening may contribute to conservation of egg cytoplasm during female meiosis. Katanin is a microtubule-severing enzyme that is concentrated at mitotic and meiotic...
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The in vivo significance of microtubule severing and the mechanisms governing its spatial regulation are not well understood. In Tetrahymena, a cell type with elaborate microtubule arrays, we engineered null mutations in subunits of the microtubule-severing complex, katanin. We show that katanin activity is essential. The net effect of katanin on the polymer mass depends on the microtubule type...
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ورودعنوان ژورنال:
- Current Biology
دوره 23 شماره
صفحات -
تاریخ انتشار 2013